The prosthetic rehabilitation of patients presenting atypical maxillary defects represents a major challenge in the field of Maxillofacial Prosthodontics. The remaining bone portions following maxillary resection, whether due to pathological conditions, trauma, or developmental disorders, often exhibit significantly reduced bone volume. For appropriate treatment planning, it is essential to understand the biomechanical behavior of the implant–prosthesis complex prior to clinical indication, particularly in cases involving limited bone availability. Implant-supported maxillofacial prostheses generally provide greater stability and retention when anchored to osseointegrated implants. In this context, the evaluation of the stress–strain environment through Finite Element Analysis (FEA) is particularly appropriate. In silico simulations can closely approximate real clinical conditions, especially when mechanically validated. The analysis proposed in this study will assess stress distribution around the implant, surrounding bone, prosthetic components, and the rehabilitative prosthesis, and will compare these findings with alternative rehabilitation approaches. The model will be generated through virtual simulation of an atypical maxillary defect and its rehabilitation using an implant-supported obturator prosthesis with a bar–clip retention system. The digital model will be obtained from computed tomography (CT) imaging of the maxillary region and subsequently remodeled through subtraction procedures. The simulation of the described defects will be performed using Rhinoceros® version 7.0, where CAD-based geometric modifications will be applied to the base model to reproduce the desired anatomical condition. The finite element mesh and biomechanical simulations will be developed using HyperWorks® 2024 software. An occlusal load will be applied to the biomechanical model in order to measure the stress and strain generated within the implant–prosthesis complex. This approach aims to predict the mechanical behavior of each component of the system and identify potential critical stress conditions. The ultimate objective of this study is to determine the clinical feasibility of this type of prosthetic rehabilitation in situations involving critically reduced maxillary bone volume

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